Generated by All in One SEO v4.9.3, this is an llms.txt file, used by LLMs to index the site. # Think PH1 Behind the Stone ## Sitemaps - [XML Sitemap](https://dev-thinkph1eu-wp2.pantheonsite.io/sitemap.xml): Contains all public & indexable URLs for this website. ## Pages - [PH1: A Metabolic Kidney Stone Disease | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/) - Primary hyperoxaluria type 1 (PH1) is a rare, progressive inherited disease that can lead to kidney function decline. Explore the disease manifestations of PH1. - [Test e diagnosi per l’iperossaluria primitiva di tipo 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/ph1-testing/) - Per formulare una diagnosi di iperossaluria primitiva di tipo 1 (PH1) si ricorre ai test genetici e alla valutazione dei livelli di ossalato. Scopri i metodi comuni per testare la PH1 nei pazienti. - [PH1: una malattia metabolica con sviluppo di nefrolitiasi | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/) - L’iperossaluria primitiva di tipo 1 (PH1) è una rara malattia ereditaria progressiva che può portare al declino della funzionalità renale. Esplora le manifestazioni della PH1. - [Pruebas y diagnóstico de la hiperoxaluria primaria de tipo 1 (HP1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/ph1-testing/) - Las pruebas genéticas y la evaluación del nivel de oxalato se utilizan para fundamentar el diagnóstico de la hiperoxaluria primaria de tipo 1 (HP1). Consulte los métodos habituales que ayudan a detectar la HP1 en pacientes. - [Tests und Diagnose der primären Hyperoxalurie Typ 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/ph1-testing/) - Zur Diagnose der primären Hyperoxalurie Typ 1 (PH1) werden Gentests und die Bestimmung des Oxalatspiegels herangezogen. Lesen Sie mehr über die gängigen Testmethoden zum Nachweis der PH1. - [Ressources supplémentaires sur l’HP1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/resources-and-support/) - Vous trouverez ici des liens vers des organisations de soutien, des informations relatives au dépistage, ainsi que du matériel pédagogique sur l’hyperoxalurie primitive de type 1 (HP1). - [Signes et symptômes de l’hyperoxalurie primitive de type 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/know-the-signs/) - Découvrez les signes et les symptômes de l’hyperoxalurie primitive de type 1 (HP1), dont les plus courants sont les calculs rénaux récurrents chez l’adulte ou la présence de calculs rénaux chez l’enfant ou l’adolescent. - [HP1 : Maladie métabolique des calculs rénaux | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/) - L’hyperoxalurie primitive de type 1 (HP1) est une maladie héréditaire rare et progressive qui peut entraîner un déclin de la fonction rénale. Découvrez les manifestations de l’HP1. - [Prise en charge médicale de l’hyperoxalurie primitive de type 1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/management/) - Découvrez les options de prise en charge médicale de l’hyperoxalurie primitive de type 1 (HP1), telles que l’hyperhydratation, le traitement par pyridoxine (vitamine B6) à haute dose et la dialyse. - [À propos de l’hyperoxalurie primitive de type 1 (HP1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/discover-ph1/) - En savoir plus sur l’hyperoxalurie primaire de type 1 (HP1), maladie génétique rare et progressive qui se manifeste souvent par la présence de calculs rénaux et peut provoquer des lésions rénales irréversibles. - [Test et diagnostic de l’hyperoxalurie primitive de type 1 (HP1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/ph1-testing/) - Le diagnostic d’hyperoxalurie primitive de type 1 (HP1) est posé en s’appuyant sur des tests génétiques et l’évaluation du taux d’oxalate. Découvrez les méthodes fréquentes permettant de dépister l’HP1 chez les patients. - [Risorse aggiuntive sulla PH1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/resources-and-support/) - Trova link per organizzazioni di advocacy, informazioni sui test e materiali didattici sull’iperossaluria primitiva di tipo 1 (PH1). - [Gestione medica dell’iperossaluria primitiva di tipo 1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/management/) - Scopri le opzioni di gestione medica per l’iperossaluria primitiva di tipo 1 (PH1), come l’iperidratazione, la terapia con dosi elevate di piridossina (vitamina B6) e la dialisi. - [Segni e sintomi dell’iperossaluria primitiva di tipo 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/know-the-signs/) - Esplora i segni e i sintomi dell’iperossaluria primitiva di tipo 1 (PH1), i più comuni dei quali includono calcoli renali ricorrenti negli adulti o calcoli renali nei bambini/adolescenti. - [Informazioni sull’iperossaluria primitiva di tipo 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/discover-ph1/) - Scopri di più sull’iperossaluria primitiva di tipo 1 (PH1), una rara malattia genetica progressiva che spesso si manifesta con calcoli renali e può causare danni renali irreversibili. - [Über die primäre Hyperoxalurie Typ 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/discover-ph1/) - Erfahren Sie mehr über die primäre Hyperoxalurie Typ 1 (PH1), eine seltene, progrediente Erbkrankheit, die häufig mit Nierensteinen einhergeht und zu irreversiblen Nierenschäden führen kann. - [Sobre la hiperoxaluria primaria de tipo 1 (HP1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/discover-ph1/) - Obtenga información sobre la hiperoxaluria primaria de tipo 1 (HP1), una enfermedad genética progresiva rara que a menudo se presenta con cálculos renales y puede causar un daño renal irreversible. - [Recursos de la HP1 adicionales | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/resources-and-support/) - Obtenga enlaces a organizaciones de apoyo, información sobre pruebas y materiales educativos sobre la hiperoxaluria primaria de tipo 1 (HP1). - [Signos y síntomas de la hiperoxaluria primaria de tipo 1 (HP1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/know-the-signs/) - Consulte los signos y síntomas de la hiperoxaluria primaria de tipo 1 (HP1), cuya variante más común incluye cálculos renales recurrentes en adultos o cualquier cálculo renal en niños/adolescentes. - [HP1: Litiasis renal metabólica | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/) - La hiperoxaluria primaria de tipo 1 (HP1) es una enfermedad hereditaria progresiva rara que puede causar un deterioro de la función renal. Consulte las manifestaciones de la HP1. - [Weitere Informationsmaterialien über die PH1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/resources-and-support/) - Nachfolgend finden Sie Links zu Patientenorganisationen und -beratungsstellen, Informationen über Diagnosetests sowie Schulungsmaterialien zur primären Hyperoxalurie Typ 1 (PH1). - [Anzeichen und Symptome der primären Hyperoxalurie Typ 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/know-the-signs/) - Lesen Sie mehr über die Anzeichen und Symptome der primären Hyperoxalurie Typ 1 (PH1), von denen die häufigsten wiederkehrende Nierensteine bei Erwachsenen oder Nierensteine bei Kindern/Jugendlichen sind. - [PH1: ein metabolisches Steinleiden | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/) - Die primäre Hyperoxalurie Typ 1 (PH1) ist eine seltene, progrediente Erbkrankheit, die zur Abnahme der Nierenfunktion führen kann. Erfahren Sie mehr über die Krankheitsmanifestationen der PH1. - [Additional PH1 Resources | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/resources-and-support/) - Find links to advocacy organisations, information on testing, and primary hyperoxaluria type 1 (PH1) education materials. - [Signs & Symptoms of Primary Hyperoxaluria Type 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/know-the-signs/) - Explore the signs & symptoms of primary hyperoxaluria type 1 (PH1), the most common of which include recurrent kidney stones in an adult or any kidney stone in a child/adolescent. - [About Primary Hyperoxaluria Type 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/discover-ph1/) - Learn about primary hyperoxaluria type 1 (PH1), a rare, progressive genetic disease that often presents with kidney stones and can cause irreversible kidney damage. - [Primary Hyperoxaluria Type 1 Medical Management | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/management/) - Learn about medical management options for primary hyperoxaluria type 1 (PH1), such as hyperhydration, high-dose pyridoxine (vitamin B6) therapy, and dialysis. - [IMPRESSUM | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/de/impressum/) - Impressum FIRMENANSCHRIFT: Alnylam Germany GmbHErika-Mann-Str. 780636 MünchenTel.: +49 89 20190100Internet: www.alnylam.deMail: info@alnylam.de GESCHÄFTSFÜHRUNG: Gilles Bertrand, Thomas Kruijver, Katarzyna WitkosAUFSICHTSBEHÖRDE: Regierung von Oberbayern, Maximilianstraße 39, 80538 MünchenHANDELSREGISTER: Amtsgericht München HRB 224597UST.ID.-NUMMER: DE 306 994 049 KONTAKT: Gilles Bertrand Alnylam Germany GmbH Erika-Mann-Str. 7 80636 MünchenTel.: +49 89 20190100Mail: info@alnylam.de - [Medizinisches Management der primären Hyperoxalurie Typ 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/management/) - Erfahren Sie mehr über medizinische Managementoptionen der primären Hyperoxalurie Typ 1 (PH1), wie z. B. Hyperhydratation, hochdosierte Pyridoxin-Therapie (Vitamin B6) und Dialyse. - [Manejo médico de la hiperoxaluria primaria de tipo 1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/management/) - Obtenga información sobre las opciones de manejo médico para la hiperoxaluria primaria de tipo 1 (HP1) como la hiperhidratación, el tratamiento con piridoxina a dosis alta (vitamina B6) y la diálisis. - [Testing & Diagnosis for Primary Hyperoxaluria Type 1 (PH1) | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/ph1-testing/) - Genetic testing and oxalate level evaluation are used to inform a primary hyperoxaluria type 1 (PH1) diagnosis. Explore the common methods to help test for PH1 in patients. - [Plan du site de l’HP1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/sitemap/) - Naviguez sur le site web Think PH1 pour en savoir plus sur l’hyperoxalurie primitive de type 1 (HP1). - [PH1 Site Map | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/sitemap/) - Navigate the Think PH1 website to learn about primary hyperoxaluria type 1 (PH1). - [Mapa del sitio de la HP1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/sitemap/) - Navegue por el sitio web Think PH1 para obtener información sobre la hiperoxaluria primaria de tipo 1 (HP1). - [Mappa del sito sulla PH1 | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/sitemap/) - Visita il sito web Think PH1 per saperne di più sull’iperossaluria primitiva di tipo 1 (PH1). - [PH1-Sitemap | Think PH1™](https://dev-thinkph1eu-wp2.pantheonsite.io/sitemap/) - Navigate the Think PH1 website to learn about primary hyperoxaluria type 1 (PH1). ## My Templates - [French Main Footer](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-footer-365) - Content area - [Italian Main Footer](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-footer-365) - Content area - [German Main Footer](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-footer-365) - Content area - [Spanish Main Footer](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-footer-365) - Content area - [Italian Error 404](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=error-404) - NON SIAMO RIESCUTI A TROVARE LA PAGINA CHE STAI CERCANDO La pagina che stai cercando potrebbe essere stata rimossa, potrebbe aver cambiato nome o potrebbe non essere temporaneamente disponibile. Prova quanto segue: Se hai digitato l'URL della pagina nella barra degli indirizzi, assicurati che sia stato inserito correttamente Apri la pagina iniziale, quindi usa la - [Error 404](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=error-404) - WE COULDN'T FIND THE PAGE YOU ARE LOOKING FOR The page you are looking for might have been removed, had its name changed, or is temporarily unavailable. Please try the following: If you typed the page's URL in the address bar, make sure that it was entered correctly Open the home page, and then use - [French Error 404](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=error-404) - NOUS N'AVONS PAS PU TROUVÉ LA PAGE QUE VOUS RECHERCHEZ La page que vous recherchez a peut-être été supprimée, son nom a changé ou elle est temporairement indisponible.Veuillez essayer la solution suivante : Si vous avez tapé l'URL de la page dans la barre d'adresse, assurez-vous qu'elle a été saisie correctement Ouvrez la page d'accueil, puis - [German Error 404](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=error-404) - Wir konnten die von Ihnen gesuchte Seite nicht finden Die gesuchte Seite wurde möglicherweise entfernt, ihr Name wurde geändert oder sie ist vorübergehend nicht verfügbar. Bitte versuchen Sie Folgendes: Wenn Sie die URL der Seite in die Adressleiste eingegeben haben, stellen Sie sicher, dass sie korrekt eingegeben wurde Öffnen Sie die Startseite und verwenden Sie - [Spanish Error 404](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=error-404) - NO PUDIMOS ENCONTRAR LA PÁGINA QUE ESTÁS BUSCANDO Es posible que la página que estás buscando haya sido eliminada, haya cambiado de nombre o no esté disponible temporalmente.Prueba lo siguiente: Si escribió la URL de la página en la barra de direcciones, asegúrese de haberla ingresado correctamente. Abra la página de inicio y luego use - [HCP popup](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=hcp-popup) - Content area - [French HCP popup](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=hcp-popup) - Content area - [German HCP popup](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=hcp-popup) - Content area - [Italian HCP popup](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=hcp-popup) - Content area - [Spanish HCP popup](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=hcp-popup) - Content area - [Main Footer](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-footer-365) - Content area - [Main header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-117) - Content area - [Search results](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-search-results-272) - Search Template: Search results Additional PH1 Resources | Think PH1™ Find links to advocacy organisations, information on testing, and primary hyperoxaluria type 1 (PH1) education materials. About Primary Hyperoxaluria Type 1 (PH1) | Think PH1™ Learn about primary hyperoxaluria type 1 (PH1), a rare, progressive genetic disease that often presents with kidney stones and can - [Spanish Mobile Menu](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=mobile-menu) - Content area - [Italian Mobile Menu](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=mobile-menu) - Content area - [German Mobile Menu](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=mobile-menu) - Content area - [French Mobile Menu](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=mobile-menu) - Content area - [Mobile Menu](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=mobile-menu) - Content area - [German Home Header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-881) - Content area - [French Main header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-117) - Content area - [Italian Main header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-117) - Content area - [Spanish Main header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-117) - Content area - [German Main header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-117) - Content area - [French Home Header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-881) - Content area - [Italian Home Header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-881) - Content area - [Spanish Home Header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-881) - Content area - [Home Header](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-header-881) - Content area - [French Search results](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-search-results-272) - Rechercher Template: French Search results Additional PH1 Resources | Think PH1™ Find links to advocacy organisations, information on testing, and primary hyperoxaluria type 1 (PH1) education materials. About Primary Hyperoxaluria Type 1 (PH1) | Think PH1™ Learn about primary hyperoxaluria type 1 (PH1), a rare, progressive genetic disease that often presents with kidney stones and - [French External warning](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=external-warning) - Content area - [Spanish External warning](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=external-warning) - Content area - [Italian External warning](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=external-warning) - Content area - [External warning](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=external-warning) - Content area - [German External warning](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=external-warning) - Content area - [Italian Search results](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-search-results-272) - Cerca Template: Italian Search results Additional PH1 Resources | Think PH1™ Find links to advocacy organisations, information on testing, and primary hyperoxaluria type 1 (PH1) education materials. About Primary Hyperoxaluria Type 1 (PH1) | Think PH1™ Learn about primary hyperoxaluria type 1 (PH1), a rare, progressive genetic disease that often presents with kidney stones and - [Spanish Search results](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-search-results-272) - Buscar Template: Spanish Search results Additional PH1 Resources | Think PH1™ Find links to advocacy organisations, information on testing, and primary hyperoxaluria type 1 (PH1) education materials. About Primary Hyperoxaluria Type 1 (PH1) | Think PH1™ Learn about primary hyperoxaluria type 1 (PH1), a rare, progressive genetic disease that often presents with kidney stones and - [Suchergebnisse](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-search-results-272) - Suche Template: Suchergebnisse Additional PH1 Resources | Think PH1™ Find links to advocacy organisations, information on testing, and primary hyperoxaluria type 1 (PH1) education materials. About Primary Hyperoxaluria Type 1 (PH1) | Think PH1™ Learn about primary hyperoxaluria type 1 (PH1), a rare, progressive genetic disease that often presents with kidney stones and can cause - [Blue button](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=blue-button) - Go to PH1 Testing - [Default Kit](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=default-kit) - [References](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=references) - References: 1. Ferraro PM, D’Addessi A, Gambaro G. Nephrol Dial Transplant. 2013;28(4):811-820. 2. Hoppe B. Nat Rev Nephrol. 2012;8(8):467-475. 3. Milliner DS, Harris PC, Sas DJ, et al. Primary hyperoxaluria type 1. GeneReviews® [Internet]. Updated 10 February 2022. Accessed June 2023. https://www.ncbi.nlm.nih.gov/books/NBK1283/ 4. Cochat P, Rumsby G. N Engl J Med. 2013;369(7):649-658. 5. Hoppe B, Kemper MJ. Pediatr Nephrol. 2010;25:403-413. 6. Jendeberg J, Geijer H, Alshamari M, Cierzniak B, Lidén - [Additional Footer](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=elementor-footer-121) - Content area - [Content item](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=content-item) - GIVEN THE PROGRESSIVE, UNPREDICTABLE NATURE OF PH1, EARLY DIAGNOSIS IS CRITICAL5,6 If PH1 is suspected, some common methods seen in clinical practice to help test for the disease are listed below. This testing information is provided for educational purposes only and is not intended to replace the independent medical judgment of any healthcare professional. Adapted - [Call out banner](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=call-out-banner) - Testing patients for PH1 See how genetic testing plays an important role in a PH1 diagnosis.3,11 Testing Options Get Updates Sign up to receive information from Alnylam about PH1 Sign Up - [White button](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=white-button) - Sign Up - [Red button](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=red-button) - More on PH1 - [Take me to button](https://dev-thinkph1eu-wp2.pantheonsite.io/?elementor_library=take-me-to-button) - TAKE ME TO DISCOVER PH1